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1

The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

Ole Thastrup, Birthe Foder, Ole Scharff

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 402 KB

english, 1987

2

Stimulation of AIDS lymphocytes with calcium ionophore (A23187) and phorbol ester (PMA): Studies of cytoplasmic free Ca, IL-2 receptor expression, IL-2 production and proliferation

Bo Hofmann, Jarl Moller, Erik Langhoff, Klaus Damgård Jakobsen, Niels Odum, Ebbe Dickmeiss, Lars P. Ryder, Ole Thastrup, Ole Scharff, Birthe Foder, Per Platz, Court Petersen, Lars Mathiesen, Tom Hartv

Journal:

Cellular Immunology

Year:

1989

Language:

english

File:

PDF, 572 KB

english, 1989

3

Changes in intracellular cAMP reported by a Redistribution® assay using a cAMP-dependent protein kinase-green fluorescent protein chimera

Kasper Almholt, Søren Tullin, Ole Skyggebjerg, Kurt Scudder, Ole Thastrup, Robert Terry

Journal:

Cellular Signalling

Year:

2004

Language:

english

File:

PDF, 661 KB

english, 2004

4

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

Ole Scharff, Birthe Foder, Ole Thastrup, Bo Hofmann, Jarl Møller, Lars P. Ryder, Klaus Damgrd Jacobsen, Erik Langhoff, Ebbe Dickmeiss, Søren Brøgger Christensen, Peter Skinhøj, Arne Svejgaard

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1988

Language:

english

File:

PDF, 533 KB

english, 1988

5

Flow injection microscopy: a novel tool for the study of cellular response and drug discovery

Ruzicka, Jaromir, Baxter, Pamela J., Thastrup, Ole, Scudder, Kurt

Journal:

The Analyst (Royal Society of Chemistry)

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

6

[Leu31,Pro34]Neuropeptide Y: A Specific Y1Receptor Agonist

Jannie Fuhlendorff, Ulrik Gether, Lars Aakerlund, Nils Langeland-Johansen, Henning Thøgersen, Steen G. Melberg, Uffe Bang Olsen, Ole Thastrup and Thue W. Schwartz

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.05 MB

english, 1990

7

The Molluscicidal Activity of Coumarins from Ethulia conyzoides and of Dicumarol

Kady, M., Brimer, Leon, Furu, P., Lemmich, Else, Nielsen, H., Thiilborg, Susanne, Thastrup, Ole, Christensen, S.

Journal:

Year:

1992

Language:

english

File:

PDF, 322 KB

english, 1992

8

Coronary Vasodilatory, Spasmolytic and cAMP-Phosphodiesterase Inhibitory Properties of Dihydropyranocoumarins and Dihydrofuranocoumarins

Thastrup, Ole, Fjalland, Bjarne, Lemmich, John

Journal:

Year:

1982

Language:

english

File:

PDF, 60 KB

english, 1982

9

Simultaneous visualization of the translocation of protein kinase Cα‒green fluorescent protein hybrids and intracellular calcium concentrations

ALMHOLT, Kasper, ARKHAMMAR, Per O.G., THASTRUP, Ole, TULLIN, Søren

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 250 KB

english, 1999

10

Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures

Árnadóttir, Sigrid Salling, Jeppesen, Maria, Lamy, Philippe, Bramsen, Jesper Bertram, Nordentoft, Iver, Knudsen, Michael, Vang, Søren, Madsen, Mogens Rørbaek, Thastrup, Ole, Thastrup, Jacob, Lindbjerg

Journal:

Molecular Oncology

Year:

2017

Language:

english

File:

PDF, 1.99 MB

english, 2017

11

Exclusion of Known Protease Activated Receptors in Factor VIIa-induced Signal Transduction

Petersen, Lars, Thastrup, Ole, Hagel, Grith, Sørensen, Brit, Freskgård, Per-Ola, Rao, L. Vijaya, Ezban, Mirella

Journal:

Thrombosis and Haemostasis

Year:

2000

File:

PDF, 122 KB

2000

12

Furocoumarin glucosides of Angelica archangelica subspecies Litoralis

Ole Thastrup, John Lemmich

Journal:

Year:

1983

Language:

english

File:

PDF, 296 KB

english, 1983

13

On the Botanical Distribution of Chiral Forms of Gossypol

Jaroszewski, Jerzy, Strøm-Hansen, Thorbjørn, Hansen, Steen, Thastrup, Ole, Kofod, Helmer

Journal:

Year:

1992

Language:

english

File:

PDF, 418 KB

english, 1992

14

Pancreatic islets cultured on extracellular matrix: An excellent preparation for microfluorometry

Per O. G. Arkhammar, Bernard R. Terry, Hans Kofod, Ole Thastrup

Journal:

Methods in Cell Science

Year:

1998

Language:

english

File:

PDF, 256 KB

english, 1998

15

Characteristics of stably expressed human dopamine D1a and D1b receptors: Atypical behavior of the dopamine D1b receptor

Ulla Bjørg Pedersen, Birgitte Norby, Anders A. Jensen, Marianne Schiødt, Annette Hansen, Peter Suhr-Jessen, Mark Scheideler, Ole Thastrup, Peter H. Andersen

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 792 KB

english, 1994

16

Coronary Vasodilatory, Spasmolytic and cAMP-Phosphodiesterase Inhibitory Properties of Dihydropyranocoumarins and Dihydrofuranocoumarins

Ole Thastrup, Bjarne Fjalland, John Lemmich

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1983

Language:

english

File:

PDF, 524 KB

english, 1983

17

Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain

Ajay Verma, David J. Hirsch, Michael R. Hanley, Ole Thastrup, S.Brogger Christensen, Solomon H. Snyder

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 367 KB

english, 1990

18

The thapsigargin-sensitive intracellular Ca2+ pool is more important in plasma membrane Ca2+ entry than the IP3-sensitive intracellular Ca2+ pool in neuronal cell lines

Haruo Takemura, Hideyo Ohshika, Noriko Yokosawa, Keiji Oguma, Ole Thastrup

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 438 KB

english, 1991

19

Structure-Activity Relationships of Analogs of Thapsigargin Modified at O-11 and O-12

Nielsen, Simon Feldbk, Thastrup, Ole, Pedersen, Rudi, Olsen, Carl Erik, Christensen, Soren Brogger

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 672 KB

english, 1995

20

Simultaneous visualization of the translocation of protein kinase Cα–green fluorescent protein hybrids and intracellular calcium concentrations

ALMHOLT, Kasper, ARKHAMMAR, Per O. G., THASTRUP, Ole, TULLIN, S⊘ren

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 250 KB

english, 1999

21

Signal Transduction via the Mitogen-activated Protein Kinase Pathway Induced by Binding of Coagulation Factor VIIa to Tissue Factor

Poulsen, Lars K., Jacobsen, Nana, Sørensen, Brit B., Bergenhem, Nils C. H., Kelly, James D., Foster, Donald C., Thastrup, Ole, Ezban, Mirella, Petersen, Lars C.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 265 KB

english, 1998

22

Dihydrofurocoumarin glucosides from Angelica archangelica and Angelica silvestris

John Lemmich, Svend Havelund, Ole Thastrup

Journal:

Year:

1983

Language:

english

File:

PDF, 401 KB

english, 1983

23

Excitation Wave Propagation as a Possible Mechanism for Signal Transmission in Pancreatic Islets of Langerhans

Aslanidi, Oleg V., Mornev, Oleg A., Skyggebjerg, Ole, Arkhammar, Per, Thastrup, Ole, Sørensen, Mads P., Christiansen, Peter L., Conradsen, Knut, Scott, Alwyn C.

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 419 KB

english, 2001

24

Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

Lars Aakerlund, Ulrik Gether, Jannie Fuhlendorff, Thue W. Schwartz, Ole Thastrup

Journal:

Year:

1990

Language:

english

File:

PDF, 671 KB

english, 1990

25

Exclusion of Known Protease Activated Receptors in Factor VIIa-induced Signal Transduction

Petersen, Lars, Thastrup, Ole, Hagel, Grith, Sørensen, Brit, Freskgård, Per-Ola, Rao, L. Vijaya, Ezban, Mirella

Journal:

Thrombosis and Haemostasis

Year:

2000

Language:

english

File:

PDF, 122 KB

english, 2000

26

Thapsigargin, a Tumor Promoter, Discharges Intracellular Ca2+Stores by Specific Inhibition of the Endoplasmic Reticulum Ca2+-ATPase

Ole Thastrup, Peter J. Cullen, Bjorn K. Drobak, Michael R. Hanley and Alan P. Dawson

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 814 KB

english, 1990

27

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relations to AIDS

Ole Scharff, Birthe Foder, Ole Thastrup, Bo Hofmann, Jarl Møller, Lars P. Ryder, Klaus Damgård Jacobsen, Erik Langhoff, Ebbe Dickneiss, Søren Brøgger Christensen, Peter Skinhøj, Arne Svejgaard

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1988

Language:

english

File:

PDF, 504 KB

english, 1988

28

Inhibition of human platelet aggregation by dihydropyrano- and dihydrofuranocoumarins, a new class of cAMP-phosphodiesterase inhibitors

Ole Thastrup, Jens B. Knudsen, John Lemmich, Kaj Winther

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 489 KB

english, 1985

29

Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA

Marks, Friedrich, Hanke, Brigitte, Thastrup, Ole, Fürstenberger, Gerhard

Journal:

Year:

1991

Language:

english

File:

PDF, 2.04 MB

english, 1991

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